Possible side effects include acne, hair loss, hair growth on the face(in women), aggressiveness, irritability, and increased levels ofestrogen.
Discontinue use and call a physician or licensed qualified health professional immediately if you experience rapid heartbeat, dizziness, blurred vision, or other similar symptoms.
When taken at higher levels, irritability, over-stimulation and fatigue have been observed. Due to its effects on the GABA receptor in the central nervous system, supplementation with pregnenolone could cause problems in people with a history of seizures.
Pregnenolone may inhibit drugs used to increase GABA activity (e.g., Neurontin); these drugs are frequently used in the treatment of epilepsy and depression.*