ButyrEn™ supplies butyrate as ButyraGen™ packaged in delayed-release vegetarian capsules.

ButyraGen™ is a tributyrin complex composed of three molecules of butyrate attached to a
glycerol backbone. After ingestion, tributyrin is hydrolyzed in the small intestine and colon to
release three butyrate molecules. The glycerol backbone is also converted to butyrate. As such,
one molecule of tributyrin yields four molecules of butyrate, enabling even modest doses of

ButyrEn™ to provide substantial amounts of butyrate.*

Butyrate is a salt of butyric acid, a short-chain fatty acid (SCFA) produced in the intestines via the bacterial fermentation of some dietary carbohydrates. Butyrate is the primary fuel for colonocytes,and adequate amounts are necessary to support the colon’s health and integrity.*
Because ButyrEn™ supplies butyrate directly and does not rely on carbohydrate fermentation, the
state of an individual’s microbiome does not impact the amount of butyrate supplied (as it might
for inulin or other prebiotics).*

In addition, as it does not require fermentation, ButyrEn™ does not cause gas and bloating in the
way prebiotics can.*
Key Featu

• Provides butyrate, a primary fuel for colonocytes*
• Supports the health and integrity of the colon*
• Does not depend on the state of an individual’s microbiome*
• Less likely to produce gas and bloating than prebiotics*